منابع مشابه
Esophageal Cancer and Bisphosphonates
Volume 2 | Issue 1 At the beginning of 2009, Dianne Wysowski of the US Food and Drug Administration summarized 23 reports of esophageal cancer following alendronate use [1]. Wysowski also noted that there had been 31 cases following alendronate use in Europe and Japan and ten cases in which other bisphosphonates had been reported as concomitant or suspect treatment. Median time from exposure to...
متن کاملOral bisphosphonates and colorectal cancer
Use of oral bisphosphonates has been associated with a decreased risk of colorectal cancer (CRC), but the association may be related to residual confounding by healthy lifestyle or body mass index (BMI). Therefore, we conducted a prospective nested case-control study within the Kaiser Permanente, Northern California health system cohort. In total, 12,505 CRC cases were individually matched to 5...
متن کاملBisphosphonates and breast cancer incidence and recurrence.
Bisphosphonates are commonly used in patients with breast cancer to reduce skeletal-related events in metastatic disease and to mitigate bone loss associated with adjuvant therapy. Preclinical studies have shown that bisphosphonates may directly inhibit breast cancer cell proliferation and metastasis. Clinical trials evaluating the oral bisphosphonate clodronate as a component of adjuvant thera...
متن کاملOral Bisphosphonates and Risk of Cancer
Bisphosphonates are currently widely used in the treatment and prevention of osteoporosis, as well as in patients with cancer metastases to bone or multiple myeloma. With a 75 million people affected by osteoporosis in the US, Europe and Japan, this represents a significant population being treated with these medications [1]. The benefits conferred by bisphosphonates in terms of reduced mortali...
متن کاملBisphosphonates, bone, and breast cancer recurrence
Bisphosphonates reduce bone turnover by inhibiting osteoclast maturation and function, and are important in the prevention of age-related osteoporosis and bone fracture, in the prevention of complications of bone metastases, and in the prevention of osteopenia and osteoporosis resulting from adjuvant aromatase inhibitor therapy of breast cancer. Over 125 years ago, in The Lancet, Paget hypothes...
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ژورنال
عنوان ژورنال: Journal of Veterinary Internal Medicine
سال: 2004
ISSN: 0891-6640,1939-1676
DOI: 10.1111/j.1939-1676.2004.tb02593.x